Biology · IGCSE 0610 · §7.1–7.5

Human Nutrition

What the body needs from food, and how the digestive system turns it into small molecules the blood can carry.

Biology · 0610 Topic 7 of 18

Diet and Nutrients

Human nutritionGetting nutrients from food into the body§7.1 · DietWhat the body needsand deficiency diseases§7.2 · Digestive systemOrgans and the fiveprocesses§7.5 · AbsorptionSmall intestine(villi are EXT)§7.3 · Physical digestionTeeth and stomachinto smaller pieces§7.4 · Chemical digestionEnzymes break moleculesinto soluble unitsthen absorbedFood is broken down so that small soluble moleculescan pass into the blood and be used by cellsphysical digestion makes surface area; enzymes do the chemistry
FIG 7.0 How the chapter connects: Food supplies the nutrients the body needs, but most food molecules are too large to enter the blood. Digestion makes them small enough, and the small intestine absorbs them.

The body needs seven kinds of dietary component: carbohydrates, fats and oils, proteins, vitamins, mineral ions, fibre and water. This page covers the three that give energy or build the body.

Definition
Balanced diet
A diet that contains all the nutrients the body needs, in the correct proportions, for its age, sex and activity.
large insoluble moleculesenzymesbreak them downchemical digestionsmall soluble molecules
FIG 7.6 Chemical digestion turns large insoluble molecules into small soluble ones.
NutrientMain sourcesImportance
CarbohydratesBread, rice, pasta, potatoes, sugarMain source of energy
Fats and oilsButter, cooking oil, oily fish, nutsEnergy source and store; insulation against heat loss
ProteinsMeat, fish, eggs, beans, milkGrowth and repair of cells and tissues

What makes a diet balanced

The amounts a person needs change with age, sex and activity. A growing child needs more protein for each kilogram of body mass than an adult, because the body is building new tissue. A person who is very active needs more energy-giving food than someone who sits all day.

A diet with too little of a nutrient, or too much of it, is not balanced. Eating more energy than the body uses is stored as fat.

Why each nutrient is needed

Carbohydrates are the main source of energy. Fats and oils also supply energy, and a layer of fat under the skin reduces heat loss. Proteins are the building material for growth and repair, because tissues such as muscle are made of protein.

Worked example (matching nutrient to need): A teenager is growing fast and has torn a muscle. Which nutrient is most important for growth and repair, and name one source. Step 1. Growth and repair of tissues is the job of protein. Step 2. Sources include meat, fish, eggs, beans and milk. Step 3. Carbohydrate and fat mainly supply energy, so they are not the answer. Answer: Protein, e.g. eggs.

Examiner note
A balanced diet is about all the nutrients in the right amounts, not only about eating less. Name the nutrient, its source and its job.
Why this matters
Too little or too much of a nutrient can cause ill health, so the right amounts matter as much as the right foods.

Vitamins, Minerals, Fibre and Water

Vitamins and mineral ions are needed in small amounts, but a shortage causes disease. Fibre and water are not nutrients that give energy, yet the body cannot work without them.

NutrientMain sourcesImportance
Vitamin CCitrus fruits, fresh vegetablesHealthy skin and gums; lack causes scurvy
Vitamin DOily fish, eggs, fortified milk; made in skin in sunlightHelps absorb calcium for bones and teeth; lack causes rickets
CalciumMilk, cheese, green vegetablesStrong bones and teeth
IronRed meat, liver, spinachMaking haemoglobin in red blood cells
Fibre (roughage)Wholemeal bread, vegetables, fruitAdds bulk so food can be moved through the gut
WaterDrinks and most foodsSolvent in cells and blood; needed for chemical reactions and transport

Deficiency diseases

A deficiency disease is caused by a lack of a nutrient in the diet. Scurvy is caused by too little vitamin C, so a diet with no fresh fruit or vegetables leads to bleeding gums and slow healing of wounds. Rickets is caused by too little vitamin D, or calcium, so children’s bones do not harden properly.

Definition
Scurvy
A deficiency disease caused by a lack of vitamin C; gums bleed and wounds heal slowly.
Definition
Rickets
A deficiency disease caused by a lack of vitamin D (or calcium); bones are soft and may bend.

Worked example (naming the cause): A child who spends little time outdoors and eats no oily fish or eggs develops soft, bent leg bones. Name the disease and the cause. Step 1. Soft, bent bones in a child are the signs of rickets. Step 2. Rickets is caused by a lack of vitamin D, which helps absorb calcium for hard bones. Answer: Rickets; lack of vitamin D.

Examiner note
State the cause as a lack of a named nutrient: scurvy is lack of vitamin C; rickets is lack of vitamin D (or calcium).
Why this matters
Fibre is not digested, but without it food moves through the gut poorly.

The Digestive System

The alimentary canal is a long tube from mouth to anus. Other organs, joined to it, add juices that help digestion.

Definition
Ingestion
The taking of substances, such as food and drink, into the body.
Definition
Egestion
The removal of undigested food from the body as faeces.
Definition
Digestion
The breakdown of food.
mouthsalivary glandoesophagusstomachlivergall bladderpancreasduodenumsmall intestineileumcolon (large intestine)rectumanus
FIG 7.1 The digestive system: the alimentary canal and its associated organs.
OrganFunction
MouthIngestion; teeth break up food; saliva starts starch digestion
Salivary glandsMake saliva containing amylase
OesophagusCarries food to the stomach
StomachChurns food; gastric juice with acid and protease
Liver and gall bladderLiver makes bile; gall bladder stores it
PancreasMakes juice with amylase, protease and lipase
Small intestineDuodenum and ileum: digestion and absorption of nutrients
Large intestineColon absorbs water; rectum stores faeces; anus egests them

Worked example (naming the process): Name the process in which cells take up glucose and use it for respiration. Step 1. Uptake and use of nutrients by cells is assimilation. Step 2. Absorption only moves nutrients into the blood. Answer: Assimilation.

Definition
Absorption
The movement of nutrients from the intestines into the blood.
Definition
Assimilation
The uptake and use of nutrients by cells.
Examiner note
Egestion is not excretion. Faeces are undigested food that was never absorbed into the body’s cells.

Physical Digestion and Teeth

Teeth and the stomach cut and crush food. This changes the size of the pieces, not the molecules in them.

incisorcuts and bitescaninetears foodpremolarcrushes and grindsmolarcrushes and grinds
FIG 7.2 The four types of tooth and what each does.

Structure of a tooth

A tooth is covered by hard enamel. Beneath it is dentine, and in the centre is the pulp, which holds the nerves and blood vessels. Cement fixes the root in the bone of the jaw, and the teeth are embedded in bone and the gums.

enameldentinepulp (nerves, blood vessels)gumcementbone of the jaw
FIG 7.3 Section through a tooth.

The stomach

The muscular wall of the stomach churns the food, which is physical digestion.

Definition
Physical digestion
The breakdown of food into smaller pieces without chemical change to the food molecules.

ExtendedBile and emulsification

Bile, made in the liver, emulsifies fats and oils: it breaks large drops into many tiny droplets. This increases the surface area for lipase, so chemical digestion is faster.

Examiner note
Say that physical digestion increases the surface area of food for enzymes. “Makes it smaller” alone is not enough.
Examiner note
Name each tooth type with its job: incisors cut, canines tear, premolars and molars crush and grind.
Why this matters
Enzymes act at the surface of food pieces, so smaller pieces are digested faster.

Chemical Digestion

Enzymes in the digestive juices break large molecules into small ones. Each type of food molecule has its own enzyme.

Definition
Chemical digestion
The breakdown of large insoluble molecules into small soluble molecules.
StarchProteinFat or oilamylasesimple sugarsproteasesamino acidslipasefatty acids and glycerol
FIG 7.4 Digestive enzymes break large molecules into small soluble ones.
EnzymeBreaks downSecreted byActs in
AmylaseStarch to simple reducing sugarsSalivary glands, pancreasMouth, small intestine
ProteaseProtein to amino acidsStomach, pancreasStomach, small intestine
LipaseFats and oils to fatty acids and glycerolPancreasSmall intestine

Hydrochloric acid

The stomach makes hydrochloric acid, part of gastric juice. It kills harmful microorganisms in food and provides an acidic pH in which the stomach enzymes work best.

Worked example (naming the products): A meal of chips is rich in starch. Name the enzyme that digests it in the mouth and the type of molecule it makes. Step 1. Starch is digested by amylase, which is in saliva. Step 2. Amylase breaks starch down into simple reducing sugars. Answer: Amylase; simple sugars.

Examiner note
Link the product to absorption: only small soluble molecules can pass from the gut into the blood.
Examiner note
Hydrochloric acid has two jobs: to kill harmful microorganisms in food and to give an acidic pH for enzymes in the stomach.
Why this matters
Starch, protein and fat are too large and insoluble to be absorbed, so they must be broken down first.

Digestion in Detail

This page is Extended content: the digestion of starch and protein in more detail, and the second job of bile.

ExtendedDigestion of starch

Amylase breaks starch down to maltose. Maltase, on the membranes of the cells lining the small intestine, then breaks maltose down to glucose, the sugar that is absorbed.

Definition
Maltose
(Extended) A sugar made of two glucose units; the product of amylase digestion of starch.
Definition
Maltase
(Extended) The enzyme that breaks down maltose to glucose, on the membranes of the epithelium lining the small intestine.

ExtendedDigestion of protein

Pepsin breaks down protein in the acidic conditions of the stomach. Trypsin breaks down protein in the alkaline conditions of the small intestine. Both are proteases.

ExtendedBile neutralises stomach acid

Bile is an alkaline mixture. It neutralises the acidic mixture of food and gastric juices entering the duodenum from the stomach, giving a suitable pH for the enzymes of the small intestine.

EnzymeWorks best atWhere
PepsinAcidic pHStomach
TrypsinAlkaline pHSmall intestine
MaltaseSmall intestine conditionsMembranes of the lining

Worked example (why bile is needed): Food leaving the stomach is acidic, but trypsin works in alkaline conditions. How does the duodenum solve this? Step 1. The mixture entering the duodenum is acidic. Step 2. Bile is alkaline, so it neutralises the acid. Step 3. This gives a suitable pH for trypsin and the other enzymes. Answer: Alkaline bile neutralises acid.

Examiner note
Match each enzyme to its pH: pepsin in the acid stomach, trypsin in the alkaline small intestine.
Examiner note
Bile is not an enzyme. It does no chemical digestion; it emulsifies fat and neutralises acid.

Absorption

Once food is digested, the small molecules must pass into the blood. This happens in the small intestine.

Where absorption happens

The small intestine is the region where nutrients are absorbed. Most water is absorbed here too, but some is also absorbed from the colon. What cannot be digested or absorbed passes to the rectum and is egested as faeces.

ExtendedVilli and microvilli

The lining of the small intestine is folded into tiny finger-like villi, and each lining cell has microvilli. These greatly increase the internal surface area for absorption.

Definition
Absorption
The movement of nutrients from the intestines into the blood.
villus (finger-like)epithelium: one cell thickcapillary networklactealmicrovilli
FIG 7.5 Structure of a villus. (EXT)

The wall of a villus is one cell thick, so absorption is fast. Capillaries carry glucose and amino acids away in the blood, and a lacteal carries fatty acids and glycerol.

Worked example (where is it absorbed?): Name the part of the alimentary canal where most nutrients are absorbed, and the part that absorbs the remaining water. Step 1. Nutrients are absorbed mainly in the small intestine. Step 2. Most water is absorbed there as well. Step 3. The remaining water is absorbed in the colon. Answer: Small intestine; colon.

Examiner note
The small intestine is where nutrients are absorbed. Most water is absorbed there too; the colon takes up the rest.
Examiner note
A villus has capillaries for glucose and amino acids, and a lacteal for fatty acids and glycerol.
Why this matters
A larger surface area for absorption means more nutrients enter the blood per second.

Following a Meal

Follow a cheese sandwich through the body to see where each process happens.

Definition
Alimentary canal
The tube from the mouth to the anus through which food passes.
OrganProcessWhat happens
MouthIngestion; physical and chemical digestionTeeth cut and crush; amylase begins to digest starch
OesophagusMovementFood is carried to the stomach
StomachPhysical and chemical digestionChurning; acid kills microorganisms; protease acts
DuodenumChemical digestionJuice from the pancreas arrives; amylase, protease and lipase act
IleumDigestion and absorptionNutrients and most water pass into the blood
ColonAbsorptionSome water is absorbed
Rectum and anusEgestionFaeces are stored then removed

The nutrients that reach the blood are then carried to the cells, where they are assimilated: glucose is used in respiration, amino acids build proteins, and fatty acids and glycerol build fats.

Product of digestionUse in the cells
GlucoseUsed in respiration to release energy
Amino acidsJoined together to make proteins
Fatty acids and glycerolUsed to make fats

Worked example (tracing a nutrient): In which organs is the starch in bread digested? Step 1. Amylase from the salivary glands acts in the mouth. Step 2. Amylase from the pancreas acts in the small intestine. Answer: Mouth and small intestine.

Examiner note
Say what happens at each organ, in order. Examiners give a mark for each correct organ and process.
Why this matters
Putting the organs in sequence shows where each process takes place, which is what most digestion questions ask.

Exam advice

Common mistakes

Confusing digestion with absorption
Digestion is breakdown. Absorption is movement of small molecules into the blood.
Confusing egestion with excretion
Egestion removes undigested food (faeces). Excretion removes waste made by cells.
Saying bile is an enzyme
Bile is an alkaline mixture that emulsifies fat and neutralises acid.
Saying most absorption happens in the stomach or colon
Nutrients are absorbed mainly in the small intestine; the colon absorbs some water.
Writing “breaks down food” without naming the product
Give the enzyme, what it digests and what it makes: amylase, starch, simple sugars.

Model answer

Describe the digestion of protein in the human alimentary canal.
[4 marks]
Mark 1
[k] Names the enzyme.
Proteases digest protein.
Mark 2
[k] Gives the product.
Protein is broken down into amino acids.
Mark 3
[k] Gives the first site.
In the stomach, where protease is secreted and acts.
Mark 4
[k] Gives the second site.
In the small intestine, using protease from the pancreas.

Recall checklist

  • Define a balanced diet.
  • Give a source and importance of each nutrient.
  • State the causes of scurvy and rickets.
  • Name the organs of the digestive system.
  • Define the five processes, from ingestion to egestion.
  • Give the roles of the four tooth types.
  • State where amylase, protease, lipase act.
  • Explain bile and the villus (Extended)

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